Reader Mr. Lu left a message in NMN's touting and real response column yesterday (2022-11-15): "I have seen a report: FDA: Anti-aging health care products NMN non-dietary supplements are reviewed with drugs!"

The article he sent was published in "Global Biotechnology" the day before, and this article was translated from FDA said ingredients studied as drug—β-NMN— is excluded from supplements (FDA Indicates that the ingredients studied as medicines — — β -NMN— — were excluded from the replenishment).

The original English text says: "In the public response to the five new dietary ingredients notices (NDINs) submitted to the FDA between the summer 2020 and spring 2022, the FDA It was not decided that NMN was excluded from dietary supplements because NMN was conducting investigations as a drug. What's more, in a letter to SyncoZymes (Shanghai) Co. Ltd. on May 16, 2022, the FDA admitted the company's ingredient notice. However, last week (2022-11-4), an FDA official told SyncoZymes that NMN was excluded from the definition of dietary supplements. "

Then, why did the FDA make such a change?

I published an article related to NMN for the first time on 2018-10-21. Magic: Living to 150 years old! , and then published NMN, HGH, nonsense tree of life on 2020-11-24. In both articles, I mentioned that NMN's marketing must be said that NMN was discovered by Harvard professor David Sinclair. But in fact, the first NMN research paper was published in 1951, and David Sinclair was born in 1969.

No matter what, David Sinclair tweeted on 2018-11-22: Any supplement company claiming that I work with them, or endorse them, is doing so illegally. I have to constantly work with lawsers to stop companies who do this. (Any supplement company that I work with them, or endorse them, is doing so illegally. I have to constantly work with lawsers to stop companies who do this.)

He tweeted on 2021-7-5: Sucks how supplement makers & other professors are profiting hugely from my research & book, with ads that supersede Lifespan when people search for it at Amazon, all while I conduct careful clinical trials. Lifespan, and at the same time I have been doing a careful clinical trial. )

As can be seen from these two Twitter, David Sinclair is extremely dissatisfied with health products businessmen using him to make money. Five months later (2021-12-1) a company called Metro International Biotech wrote a letter to the FDA: "As a company that has conducted public clinical trials with β-NMN, we ask the FDA to treat the Federal Food, Drugs and Cosmetics Act seriously (201(ff) ”

According to Metro International Biotech's website, the company is conducting a Phase II clinical trial of NMN, and David Sinclair is the company co-founder and consultant chairman. From this, it can be seen that the reason why the FDA banned the sale of NMN supplements this month was because David Sinclair was unwilling to see his hard work continue to be used by health care providers to make a fortune..

Please note: During the search process, I saw a Quantitative Analysis of Twenty-Two NMN Consumer Products published on 2021-10-20. This is a test of 22 NMN brands sold in Amazon by a company called ChromaDex. It turned out that among these brands, 14% NMN content exceeded the label’s claim, 23% were slightly lower than the label’s claim (about 88-99%), 64% were less than the detection limit (i.e. 1% lower than the label’s claim), and 14% of brands were completely unable to detect NMN. (ChromaDex is a company invested by Li Jiacheng. Please see Li Jiacheng's eternal medicine)

Original text: Why does the FDA ban NMN supplementation drugs?